If you have high blood cholesterol, making lifestyle changes is a great first step to lower your risk of heart disease. The main goal of treatment is to lower, or control, your LDL level to minimize your personal risk for heart attack or cardiovascular disease, based on your cholesterol numbers and other risk factors, such as a history of cardiovascular disease. Moderate physical activity can help raise high-density lipoprotein (HDL) cholesterol, the "good" cholesterol. There’s a new drug called Nexletol, and it’s used for people with the highest risk. New Treatments for High Cholesterol. Usually, the first line of treatment for high cholesterol is lifestyle modification, but if you have FH you’ll need more advanced treatment. The following products are considered to be alternative treatments or natural remedies for High Cholesterol. If those steps don’t reduce your risk enough, your doctor may prescribe medications to help. Continued. Make the changes worth making. What is cholesterol? Triglycerides: Another type of fat in your blood. Apple cider vinegar possesses pectin and acetic acid. A variety of medications are also available to lower high cholesterol. Adults 40-75 years of age with an LDL-C 70-189 mg/dL without clinical ASCVD or diabetes and an estimated ten-year ASCVD risk ≥ 7.5% should be treated with moderate- to high-intensity statin therapy. Using apple is considered one of the best natural home remedies for high cholesterol levels. Treatment Only one in three people who have high LDL cholesterol have the condition under control. Exercise can improve cholesterol. The American Heart Association explains how cholesterol affects the heart. Cholesterol is a waxy, fat-like substance that the liver produces. HDL cholesterol: The "good" cholesterol that lowers your risk for heart disease. Medications Besides Statins for Lowering Cholesterol. With your doctor's OK, work up to at least 30 minutes of exercise five times a week or vigorous aerobic activity for 20 minutes three times a week. Having a healthy lifestyle is crucial for heart health and for overall health,” says Martin. “It’s always important to eat a low-fat diet, exercise and control your weight. High Cholesterol, Familial Homozygous (14 drugs) Hyperlipoproteinemia (151 drugs in 6 topics) Hypertriglyceridemia (26 drugs) Niacin Flush (19 drugs) Sitosterolemia (2 drugs) Alternative treatments for High Cholesterol. That means they’re usually the first medication providers will consider when recommending a cholesterol-lowering treatment. For example, your doctor may prescribe: statins (lovaststin, atorvastatin) cholesterol absorption inhibitors (cholestyramine) For years, statins have been the drug of choice when it comes to treating high cholesterol, and that remains the case today. 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